Overview of Poultry Eimeria Life Cycle and Host-Parasite Interactions

Rabies Infection: An Overview of Lyssavirus-Host Protein Interactions

Viruses are obligatory intracellular parasites that use cell proteins to take the control of the cell functions in order to accomplish their life cycle. Studying the viral-host interactions would increase our knowledge of the viral biology and mechanisms of pathogenesis. Studies on pathogenesis mechanisms of lyssaviruses, which are the causative agents of rabies, have revealed some important ho...

The Apicomplexan Parasite, Eimeria falciformis, Co-opts Host Tryptophan Catabolism for Life Cycle Progression in the Mouse

The obligate-intracellular apicomplexan parasites e.g. Toxoplasma gondii and Plasmodium species induce an IFNγ-driven induction of host indoleamine-2,3-dioxygenase (IDO), the first and rate-limiting enzyme of tryptophan catabolism in the kynurenine pathway. Induction of IDO1 underlies depletion of subcellular tryptophan in host cells, which is proposed to inhibit the in vitro growth of suscepti...

Cancer and life-history traits: lessons from host-parasite interactions.

Despite important differences between infectious diseases and cancers, tumour development (neoplasia) can nonetheless be closely compared to infectious disease because of the similarity of their effects on the body. On this basis, we predict that many of the life-history (LH) responses observed in the context of host-parasite interactions should also be relevant in the context of cancer. Parasi...

Parasite-host Interactions

Holobiont–Holobiont Interactions: Redefining Host–Parasite Interactions

The term holobiont (Greek, from holos, whole; bios, life; -ont, to be; whole unit of life) describes a long-term physical association between different living organisms [1]. Theoretically, this definition encompasses all symbiotic associations (along the mutualism–parasitism continuum) spanning all taxa. However, in most cases, the term holobiont is restricted to the host and its associated mut...